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AMAZO Android pawn of Professor Ivo with the entire powers of the Justice League of America.
Obsessed with the idea of achieving immortality, the villainous Professor Ivo constructed a special android in the hopes that it would defeat the Justice League and be a testament to his genius. Using special absorption cells, Amazo became charged with the stolen super powers of the entire Justice League of America. First Appearance: Brave And The Bold Vol.1 #30
     
ASMODEL Formerly the leader of the Bull Host Angels of Heaven, he allied himself with Neron and has faced the League several times.

In heaven, the angel Asmodel was formerly the Lord Harrier of the Bull Host, and Commander of the Cherubim Alpha Battalion. He was the highest ranked and most feared of the Pax Dei, the Angel Army of heaven, but grew tired of simply being a servant of God. Rebelling as Lucifer had millennia before, Asmodel waged war against the forces of heaven. First Appearance: JLA Vol.1 #7
     
DARKSEID Despot ruler of Apokolips, his search for the Anti-Life Equation has brought him into conflict with League many times.
Prince Uxas was the son of Queen Heggra of Apokolips. He planned to gain the throne at any cost. Second in line to the throne behind his brother Drax, Uxas created political upheaval while his brother attempted to make peace with the nearby world of New Genesis. When Drax attempted to claim the fabled Omega Force and assume godhood, Uxas murdered him and claimed the power for himself. Renaming himself Darkseid after the apocryphal god. First Appearance: Superman's Pal, Jimmy Olsen Vol.1 #134
     
DESPERO The tyrant of Kalanor, Despero is a frequent opponent to the League with his psionic abilities.
On Despero's home world of Kalanor, the people of the world were much like humans. They developed a nuclear energy source of incredible power. Many thought this new power was dangerous but the warnings were ignored and the planet was ravaged by high energy plasmas. Most of the species of Kalanor were eradicated, but those that survived were mutated into entirely different beings. Despero's race emerged and quickly became dominant through telepathic subjugation of the other species. There was much unrest on Kalanor and war brought Despero's father victory. When Despero was of age, he killed his father and took control of Kalanor. First Appearance: Justice League America Vol.1 #1
     
DOCTOR LIGHT A scientist turned villain, he went on to fight the League repeatedly before menacing the Teen Titans.
Dr. Arthur Light was a scientist at STAR Labs, partnered with Jacob Finlay. Finlay had used a technically advanced suit to control light as a small-time superhero, but he was accidentally killed by Arthur Light while his career was still taking off. Arthur took the suit and the "Doctor Light" name and used them for criminal means. First Appearance: Justice League America Vol.1 #12
     
DOCTOR DESTINY A criminal scientist using his superior mind and dreaming powers to attack the Justice League.
Dr. Destiny was once a petty criminal scientist who used his genius to create astounding devices for crime. He created the Materioptikon, a device that, allowed him to create reality from the fabric of dreams. First Appearance: Justice League America Vol.1 #5
     
DOOMSDAY Doomsday is the ultimate weapon that seeks Kryptonians and their demise. This task has brought him into conflict with the League many times.
Doomsday was engineered and evolved on Krypton. Long before intelligent life had evolved and the planet became habitable a genetic engineer called Bertron came to Krypton. Bertron built a laboratory there and began an experiment to create the ultimate life form. Bertron took an infant and threw it out of the laboratory into the hostile environment of Krypton were hideous creatures tore it to pieces. The remains of that child were collected and a new child cloned. Bertron and his team repeated this process for over thirty years each day killing the child and re-cloning him. Over the years the child evolved to meet the needs of the hostile environment outside and eventually overcame it. First Appearance: Superman: The Man Of Steel Vol.1 #17
     
ECLIPSO The original incarnation of the Spirit of Wrath, who has clashed withe the Justice League on a number of occassions.
Eclipso is the original incarnation of the Spirit of Wrath, who was removed from his position by his replacement the Spectre and imprisoned in a black crystal known as The Heart Of Darkness. Eclipso has the ability to possess anyone who owns the crystal. First Appearance: House of Secrets Vol.1 #61
   
   
GAMEMNAE An ancient Atlantean sorceress who brought the JLA thousands of years into the past to destroy them.
Gamemnae is an Atlantean sorceress who was born 3,000 years ago. She was cast from her home as a child because of her blonde hair, a terrible curse in Atlantean myth. She enslaved the people of Atlantis, raised it to the surface, and formed a league of Ancient heroes to defeat the "Seven Headed Serpent" from a prophecy, the Justice League of America. First Appearance: JLA Vol.1 #70
   
THE GENERAL A military man who didn’t trust super-heroes, finally became a physical threat after possessing the body of the Shaggy Man.
Air Force General Wade Eiling never trusted super heroes and is obsessed with maintaining a meta-human ‘Balance Of Power’. He created the Ultramarine Corps as part of this. Discovering that he had an inoperable brain tumour, he enlisted the Ultramarine Corps to find a replacement body. Eiling’s choice was the Shaggy Man, a being created by Professor Zagarian out of adaptive ‘Plastalloy’. Eiling had his mind transferred into the Shaggy Man and began his plans for world domination. First Appearance: Captain Atom Vol. 3 #1
   
KANJAR RO An intergalactic dictator who forced the Justice League Of America to fight his enemies
Kanjar Ro is the dictatorial felon of the planet Dhor, a world in the Antarean star system. His army waged wars with neighbouring worlds Alstair, Mosteel and Llar, each ruled by tyrants desiring total control of their galaxy. To tip the balance of power in his favour, Kanjar Ro travelled to earth and forced the justice League Of America to fight his enemies to save the people of Earth. First Appearance: Justice League Of America Vol.1 #3
   
LIBRA Due to his childhood, Justin Ballantine grew up to cherish the idea of balance, especially between good and evil. He led the Injustice Gang.
Libra was born Justin Ballantine, he lost his mother at the age of eight due to an alcoholic pharmacist incorrectly weighing the medicine his mother needed. Soon after his father turned to alcoholism and brutally abused Justin regularly. Justin would later use all the money he had to buy a telescope so that he could stargaze and imagine a better life among the stars. His father came to the roof and threatened to beat him with his telescope one night but he lost his balance and fell to his death, which left Justin with the unhealthy idea that "life is just a matter of balance". This notion became an obsession that defined his super-villain career. First Appearance: Justice League Of America Vol.1 #111
   
MAGEDDON Mageddon is a war machine, created by the Old Gods, It was made to make sentient lifeforms destroy each other.
In a forgotten time, well before the birth of the universe, Mageddon was created by the Old Gods of Urgund, beings who destroyed themselves with weapons capable of rending infinity to pieces. Mageddon survived. After 15 billion years chained in a gravity sink on the outer curve of space time, it crawled from it’s prison and lurched across the cosmos toward Earth. First Appearance: JLA Vol.1 #37
   
PROMETHEUS A violent sociopath who has sworn to annihilate the forces of justice.
A child of love born to sociopathic parents that were thieves and violent criminals on the run from the law. They were both killed during a police chase. It was on that day that Prometheus’s hair turned white and he swore that he would annihilate the forces of justice. Using his parent’s money and criminal contacts, he trained and established a new identity as Prometheus. First Appearance: New Year's Evil: Prometheus #1
   
QUEEN BEE An insectoid Queen, intent on enslaving worlds.
Queen Bee is the Royal Genetrix of an insectoid species from the planet Kroll. The race is trillions strong and moves from galaxy to galaxy enslaving worlds converting the inhabitants into drone slaves. First Appearance: Justice League of America Vol.1 #23
   
   
QUEEN OF FABLES Exiled from her dimension, the Queen of Fables drew the JLA into a fairy tale world.
The Queen of Fables is the wickedest of witches, a sorceress from another dimension exiled to Earth as punishment for her great evils. Before science and fact overcame superstition and fear, the Queen menaced mankind with Dragons, Ogres and Fairies. First Appearance: JLA Vol.1 #47
   
SOLARIS A man-made tyrant sun who sought to conquer two eras, By encoding its evil in a techno-virus sent back to infect 20th century machinery.
Solaris is a stellar super computer hailing from the 853rd century. The man made tyrant sun sought to conquer the 853rd century and the 20th century by encoding it’s evil in a techno-virus sent back to infect 20th century machinery, literally creating himself. First Appearance: DC One Million #1
   
STARBREAKER A cosmic vampire that feeds off the energy of stars, planets and negative emotional states.
Starbreaker is an ancient being older than all of creation, he is the subject of legends on countless worlds describing the end of the universe. In eons past, he has laid waste to entire galactic clusters. First Appearance: Justice League of America Vol.1 #96
   
WHITE MARTIANS Cruel alien invaders that were imprisoned in the ‘Stiil Zone’. They waited for an opportunity to reclaim the Earth as their own!
The White Martians and the Green Martians were originally part of the same race, known as "The Burning". This race used fire to reproduce asexually and were belligerent to all. 20,000 years ago, The Guardians of the Universe, fearing the ruthless Martians, genetically split them into two distinct species, white and green. The Green Martians were peaceful philosophers; the White Martians were savage warriors. A lengthy civil war between the two races ended when the few surviving White Martians were rounded up and exiled to the extra-dimensional "Still Zone". First Appearance: JLA Vol.1 #47