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| Defenders Villains | ||
| Attuma | Bi-Beast | Black Dragon |
| Calizuma | Dormammu | Dragon Of The Moon |
| Executioner | Gargantua | Korvac |
| Looter | Lorelei | Mandrill |
| Mad-Dog | Mephisto | Nameless One |
| Nightmare | Null the Living Darkness | Over-Mind |
| Pluto | Presence | Professor Power |
| Red Ghost | Satannish | Sons Of The Serpent |
| Van Nyborg | Xemnu | Yandroth |
| A.I.M | ||
| A.I.M | MODOK | |
| Brotherhood Of Evil Mutants I | ||
| Blob | Lorelei I | Magneto (Leader) |
| Mastermind I | Unus the Untouchable | |
| Deep Six | ||
| Attuma (Leader) | Nagala | Orka |
| Piranha | Tiger Shark | |
| Emissaries Of Evil I | ||
| Cobalt Man | Egghead (Leader) | Rhino |
| Solarr | ||
| The Headmen | ||
| Chondu | Gorilla man | Ruby Thursday |
| Shrunken Bones | ||
| Offenders | ||
| Baron Mordo | Red Hulk | Terrax |
| Tiger Shark | ||
| Squadron Sinister I | ||
| Doctor Spectrum II | Hyperion II | Nighthawk II |
| Whizzer IV | ||
| Wrecking Crew | ||
| Bulldozer | Piledriver | Thunderball |
| Wrecker (Leader) | ||
| Zodiac II | ||
| Aries V | Cancer II | Capricorn II |
| Leo II | Libra II | Pisces II |
| Sagittarius II | Scorpio I (Leader) | |